DRUG DISCOVERY & THERAPY WORLD CONGRESS 2019

**DAY 1: Monday, July 10, 2017**
DRUG DISCOVERY & THERAPY WORLD CONGRESS 2017 and Global Biotechnology Congress 2017 July 10^th – 13^th, 2017, Westin Copley Place, Boston, MA, USA www.ddtwc.com / www.globalbiotechcongress.com
TIME	INAUGURAL PROGRAM ::: Location: Essex Center ::: 3^rd Floor
8:25 - 8:30 am	Guests to be Seated
8:30 - 8:40 am	Welcome Remarks by Chairmen Organizing Committee		Prof. Ferid Murad (Nobel Laureate) and Prof. Atta-ur-Rahman, FRS
Chairman: A.D. MacKerell, Jr. Co-Chairman: Atta-ur-Rahman	JOINT PLENARY SESSION ::: Location: Essex Center ::: 3^rd Floor
Time	Speakers	Titles
8:40 - 9:25 am	Stephen Joseph Elledge *PL-1*	Aneuploidy Promotes Cell Proliferation and Inhibits Immune Surveillance *
9:25 - 10:10 am	Kenneth Carl Anderson *PL-2*	*Targeting Achilles Heels in Myeloma*
COFFEE & SOCIAL MIXER (Location: Essex Foyer – 3^rd Floor): 10:10 – 10:40 AM

Locations		Lecture Hall St. George A & B 3^rd Floor	Lecture Hall St. George C 3^rd Floor	Lecture Hall St. George D 3^rd Floor
Tracks		Pharmaceutical Research & Development	Drug Delivery & Targeting	Plant & Environment
		Anti-Infectives
		Translational Medicine
		*In-silico* *Drug Design and In-silico* Screening**
Chairman: R. Chaguturu Co-Chairman: C. Gonzalez-Bello			Chairman: B. Kleuser Co-Chairman: M. Schäfer-Korting	Chairman: M. Ohme-Takagi Co-Chairman: R. Bensen
10:40 - 11:15 am			10:40 - 11:10 am	10:40 - 11:10 am
*KNL-3* Rathnam Chaguturu *Drug Discovery Efforts Mirror the Proverbial Hyper Cycle: What’s Next?*			*IL-4* Monika Schäfer-Korting *Rethinking Drug Development – Improving Translational Research*	*IL-5* Masaru Ohme-Takagi *Negative Regulations Play a Role as “Keystones” for the Control of Physiological Activities in Plants*
11:15 - 11:35 am			11:10 - 11:30 am	11:10 - 11:30 am
*SL-6* Mario Milani *The Difficult Path Toward Knowledge: An Ongoing Story on New Dengue Virus Inhibitors*			*SL-7* Burkhard Kleuser *Crosstalk Between Core-multishell Nanocarriers and Antigen-presenting Cells of the Skin*	*SL-8* Robert Bensen *Improving Drought Tolerance in Crop Plants: An Industry Perspective*
11:35 - 11:55 am			11:30 - 11:50 am	11:30 - 11:50 am
*SL-9* Concepción González-Bello *Freezing the Essential Motion of Key Bacterial Enzymes – A Strategy for Antibiotic Drug Discovery*			*SL-10* Christian Zoschke *The Barrier Function of Organotypic Non-melanoma Skin Cancer Models*	*SL-11* Tomokazu Kawashima *Extended Comparative Genomics to Identify Agriculturally Useful Genes in Plants*
11:55 - 12:15 pm			11:50 - 12:10 pm	11:50 - 12:10 pm
*SL-11(a)* Yanxiang Zhao *Molecular Mechanism of β-lactamases and Implication for Antibiotic Resistance*			*SL-13* Muhammad Qadir *Novel Radiolabeled Polydentate Ligands as Potential Diagnostic Probes*	*SL-14* Brian Vande Berg *Trait Components to Support an Integrated R&D Strategy*
12:15 - 12:35 pm			12:10 - 12:30 pm	12:10 - 12:30 pm
*SL-12* Roman Maciej Kalina *Placebo Effect as Starting Point of the Use of Innovative Agonology in the Therapy and Treatment*			*SL-16* Ajit Sharma *Drug Entrapment in Dendrimers*	*SL-17* Masami Yokota Hirai *Metabolomics-based Studies for Understanding of Plant Metabolism*
12:35 - 12:55 pm			12:30 - 12:50 pm	12:30 - 12:50 pm
*SL-15* Ravindranath Singh Rathore *Novel Dual-binding Cation-π Inhibitors of AChE: Design, Synthesis and Biological Evaluation* *(Withdrawn)*			*SL-18* Eckart Ruehl *Topical Drug Delivery into Skin Probed by Label-free Spectromicroscopy*	*SL-19* Ling Yuan *Plant Genome Editing for the Production of Valuable Proteins*
			12:50 - 1:10 pm	12:50 - 1:10 pm
			*SL-20* Ulrike Alexiev *Advanced Time-resolved Fluorescence Microscopy for Investigating Nanocarrier and Drug Delivery*	*SL-20(a)* Zhaohua Peng *Proteome-wide Analysis of Lysine 2-hydroxyisobutyrylation in Developing Rice (Oryza sativa) Seeds Reveals Unique Sequence Feature of Modification Sites and Functions in Seed Development*
LUNCH BREAK (Location: Essex South – 3^rd Floor): 1:00 – 2:30 PM
Locations	Lecture Hall St. George A & B 3^rd Floor		Lecture Hall St. George C 3^rd Floor	Lecture Hall St. George D 3^rd Floor
Tracks	Proteomics & Bioinformatics		Genomics	Regenerative Medicine
			Recent Advances in Patient Treatment and Care
	Medical Imaging		Hot Topics in Drug Targets
	Drug Discovery in Preclinical Research
	Biologics
Chairman: F. Huq Co-Chairman: M. Younus			Chairman: Van S. Kristel Co-Chairman: H.M. Sobell	Chairman: I. Roy Co-Chairman: M. Tosun
2:30 - 3:00 pm			2:30 - 3:00 pm	2:30 - 3:05 pm
*IL-21* Fazlul Huq *Tumour* *Active Phytochemicals Found to Enhance Platinum Action in Ovarian Tumour Models*			*IL-22* Henry Martinique Sobell *The Centers of Premeltons Signal the Beginning and Ends of Genes*	*KNL-23* Ali Khademhosseini *Nano- and Microfabricated Hydrogels for Regenerative Engineering*
3:00 - 3:20 pm			3:00 - 3:20 pm	3:05 - 3:25 pm
*SL-24* Yi Zhang *In Vivo Imaging of Neuxial Inflammation in Sciatica Pain with PET/MRI*			*SL-25* Doris Vandeputte *The Gut Microbiome in Health and Disease, The Importance of Quantitative Microbiome Profiling*	*SL-26* Nassim Halim Abi Chahine *The Regentime Procedure, A Safe Way for Regeneration*
3:20 - 3:55 pm			3:20 - 3:40 pm	3:25 - 3:45 pm
*KNL-27* Muhammad Iqbal Choudhary *New Pharmacophores from Medicinal Plants* *(Withdrawn)*			*SL-28* Van Steen Kristel *Systems Genetics for Precision Medicine*	*SL-29* Bruno Delorme *The Concept of Mesenchymal Stem Cells: From Their Discovery to Innovative MSC-derived Therapies*
3:55 - 4:15 pm			3:40 - 4:00 pm	3:45 - 4:05 pm
*SL-30* Tatsuya Takimoto *Study on the Correlation Between Structures of Bithiazole Derivatives and Plasmid DNA Cleavage Activity by Using Simulation and Experiment*			*SL-31* Fentaw Abegaz *Epistasis Detection for Human Complex Diseases in Structured Populations*	*SL-32* Hae Lin Jang *An Explanation of the Ratio Between Hydroxyapatite and Whitlockite in Bone: Interplay of the Two Major Nanocrystals for Bone Formation*
4:15 - 4:35 pm			4:00 - 4:20 pm	4:05 - 4:25 pm
*SL-33* Maayan Gal *Computational and Biophysical Tools Towards PPIs Drug Discovery*			*SL-34* William Joseph Rowe *Neil Armstrong Syndrome and Thermoregulation*	*SL-35* Metiner Tosun *Functional Genomics Analysis of Hepatocellular Tumor-initiating Cells*
4:35 - 4:55 pm			4:20 - 4:55 pm	4:25 - 4:45 pm
*SL-36* Muhammad Younus *Lead Residues in Lohi Sheep: A Hemato-biochemical and Histopathological Study*			*KNL-37* Simon Christopher Robson *The Ectonucleotidase CD39 is a Checkpoint Inhibitor Target in Cancer*	*SL-38* Jung Park *Electric Field-guided Stem Cell Differentiation on TiO₂ Nanotubular Surfaces*
COFFEE BREAK (Location: Essex Foyer – 3^rd Floor): 5:00 - 5:30 PM

**DAY 2: Tuesday, July 11, 2017**
Chairman: I. Nagy Co-Chairman: I.J. McEwan		JOINT PLENARY SESSION ::: Location: Essex Center ::: 3^rd Floor
Time	Speakers		Titles
9:00 - 9:45 am	*PL-39* Shuji Ogino		*Emerging Pharmaco-MPE (Molecular Pathological Epidemiology) and Immuno-MPE For Precision Medicine*
9:45 - 10:30 am	*PL-40* Rudolf Jaenisch		*Epigenetics, Stem Cells and Disease Research*
COFFEE & SOCIAL MIXER (Location: Essex Foyer – 3^rd Floor): 10:30 - 11:15 AM

Locations		Lecture Hall St. George A & B 3^rd Floor	Lecture Hall St. George C 3^rd Floor	Lecture Hall St. George D 3^rd Floor
Tracks		Innovative Drug Discovery and Nanotechnology	Protein & Peptide Sciences	Pharmaceutical Biotechnology
		High-throughput Screening & Laboratory Automation		Industrial and Manufacturing
Chairman: T.J. Webster Co-Chairman: A. Mazzaglia			Chairman: E.B. Thompson Co-Chairman: I.J. McEwan	Chairman: A. Gravanis Co-Chairman: S. Suchkov
11:15 - 11:50 am			11:15 - 11:45 am	11:15 - 11:35 am
*KNL-41* Thomas Jay Webster *The Age of “Nano-biotics”: Self-assembled Materials as Novel Antibacterial Agents Against Drug-resistance Bacteria*			*IL-42* Elizabeth Brad Thompson *Protein Intrinsic Disorder in Drug Design and Use*	*SL-43* Sergey Suchkov 2^nd Lecture *PM (Personalized Medicine) as a New Model of National and International Healthcare Services to Secure a Biosafety of the Society*
11:50 - 12:20 pm			11:45 - 12:05 pm	11:35 - 12:05 pm
*IL-44* Antonino Mazzaglia *Nanomaterials Based on Cyclodextrin: Design, Advances in (Photo) Therapeutics Delivery and Bio-performances*			*SL-45* Collin Stultz *Dynamics of Alpha-synuclein Aggregation*	*IL-46* Achilleas Gravanis *Synthetic Microneurotrophins in Brain Protection and Function*
12:20 - 12:40 pm			12:05 - 12:25 pm	12:05 - 12:40 pm
*SL-47* Keiichi Motoyama *Potential Use of Cyclodextrin Derivatives as Therapeutic Agents for Lysosomal Storage Disorders*			*SL-48* William Austin Elam *A Protein Stabilizing Osmolyte Restores Mutant Glucocorticoid Receptor Binding*	*KNL-49* M. Amin Arnaout *Structure-based therapeutic Targeting of Integrins* *(Withdrawn)*
12:40 - 1:00 pm			12:25 - 12:45 pm	12:40 - 1:00 pm
*SL-50* Ravindra Peravali *Drug Discovery and Testing Using High-throughput Morphological and Behavioral Screening of Zebrafish Larvae* *(Withdrawn)*			*SL-51* Lidija Covic *Pepducins* *as Allosteric Agents and Therapeutics to Prevent Coronary Artery Thrombosis and NASH*	*SL-52* Weiwen Zhang *Synthetic Biology of Photosynthetic Cyanobacteria: Regulation of Tolerance*
			12:45 - 1:05 pm
			*SL-53* Iain Joseph McEwan *The Intrinsically Disordered Amino Terminal Domain of Steroid Hormone Receptors as a Novel Drug Target: Identification of Small Molecule Inhibitors*
LUNCH BREAK (Location: Essex South – 3^rd Floor): 1:00 - 2:30 PM
Locations	Lecture Hall St. George A & B 3^rd Floor		Lecture Hall St. George C 3^rd Floor	Lecture Hall St. George D 3^rd Floor
Tracks	Innovative Drug Discovery and Nanotechnology		Protein & Peptide Sciences	Pharmaceutical Biotechnology
	Chemistry / Combinatorial Chemistry		Drug Discovery in Preclinical Research	Plant & Environment
	Diabetes and Obesity Drug Discovery and Therapy
Chairman: K. Motoyama Co-Chairman: G. Gouhier			Chairman: P.B. Watkins Co-Chairman: I. Nagy	Chairman: H.-Q. Ling Co-Chairman: J. Nilvebrant
2:30 - 2:50 pm			2:30 - 2:50 pm	2:30 - 2:50 pm
*SL-54* Géraldine Gouhier *Cyclodextrins: An Appropriate Scaffold for New MRI Theranostic Probes***			*SL-55* Jing Li *Intrinsic Disorder and Allostery in Glucocorticoid Receptor*	*SL-56* Johan Nilvebrant *Antibody Libraries Based on An Autonomous Human Variable Domain*
2:50 - 3:10 pm			2:50 - 3:10 pm	2:50 - 3:10 pm
*SL-57* Lajos Szente *Therapeutic and Diagnostic Utility of Cyclodextrin Derivatives*			*SL-58* Raj Kumar *Role of Site-specific Phosphorylation in the Action of Glucocorticoid Receptor*	*SL-59* Walter Schubert *Tissue Worlds2.0: MUS-ICR Robotics Decoding the Dark Space of Diseases-Experience with ALS to Therapy*
3:10 - 3:30 pm			3:10 - 3:30 pm	3:10 - 3:30 pm
*SL-60* Valentina Rapozzi *Innovative Drugs in Photodynamic Therapy*			*SL-61* Lei Li *Discovery and Pharmacological Evaluation of Novel Caeridins with Smooth Muscle Activities, Isolated from the Skin Secretion of the Australian White’s Tree Frog, Litoria caerulea*	*SL-62* Sergey Suchkov *Antibody-proteases as a Novel Biomarker and Thus the Unique Target to Manage Demyelination: A Green Light to be Opened for Biopharma*
3:30 - 3:50 pm			3:30 - 4:00 pm	3:30 - 3:50 pm
*SL-63* Keiichi Motoyama *Mitophagy-mediated Novel Cell Death Induced by Folate-appended Methyl-β-cyclodextrin***			*IL-64* Istvan Nagy *Integrated Approach to Identify New Targets for Analgesics for Burn Injury-associated Pain*	*SL-65* Leyanis Rodríguez Vera *Pharmacometric* *Approach to Support Dosing Strategy of Nimotuzumab in Patients with Breast Cancer*
3:50 - 4:10 pm			4:00 - 4:20 pm	3:50 - 4:10 pm
*SL-66* José García Suárez *Production of a Novel Recombinant Polypeptide from Serratia marcescens for Cancer Therapy*			*SL-67* Peter Juhasz *Target Discovery from Phenotypic Screens and Known Compounds of Unknown Target*	*SL-68* Evan Bennett Siegel *Advancing New Biotechnology Products into Clinical Trials and Marketing Applications*
4:10 - 4:30 pm			4:20 - 4:40 pm	4:10 - 4:40 pm
*SL-69* Mostafa Mostafa Abo Elsoud *Effect of Gamma Irradiation on Biogenic Production of Tellurium Nanoparticles* *(Withdrawn)*			*SL-70* Sini Junttila *Bioinformatic* *Next Generation Sequencing Data Analysis Workflow for Preclinical Studies*	*IL-71* Hong-Qing Ling *Molecular Regulation Mechanisms of Iron Uptake and Homeostasis in Plants*
4:30 - 4:50 pm			4:40 - 5:00 pm	4:40 - 5:00 pm
*SL-72* Shamshad Begum Quraishi *A New Approach for Diagnosis of Wilson’s Disease and Bangladesh Perspective*			*SL-73* Paul B. Watkins *Using Quantitative Systems Toxicology (QST) to Assess Drug Safety: The Experience of the DILIsim Initiative*	*SL-74* Junhua Peng *Solar Radiation and Adaptive Genetic Differentiation in Wild Emer Wheat, Triticum dicoccoides*
4:50 - 5:10 pm			5:00 - 5:20 pm	5:00 - 5:20 pm
*SL-75* Ying Wang *Chemistry in the Fast Lane-enabling Technologies for Drug Discovery*			*SL-76* Laszlo Urban *Translational Aspects of Secondary Pharmacology*	*SL-77* Huixia Shou *Regulation of Phosphate Homostasis via the Ubiquitin-conjugating E2 Enzyme, PHO2 and a RING-type E3 Ubiquitin-ligase, OsNLA1 in Rice*
5:10 - 5:30 pm			5:20 - 5:40 pm	5:20 - 5:40 pm
*SL-78* Maria Grishina *www.ChemoSophia.com On-line Computational Services for In silico Drug Design and Screening*			*SL-79* Graham Dempsey *All-optical Electrophysiology for Neuroscience and Cardiovascular Drug Discovery*	*SL-80* Qian-Hua Shen *Barley Interaction with Powdery Mildew Fungus: How Protein Kinases Regulate Defense Transcriptions*
5:30 - 5:50 pm
*SL-81* Tarek Mahmoud Mahfouz *Small Molecule Affinities for Sirt-1 Deacetylase Enzyme*
COFFEE BREAK (Location: Essex Foyer – 3^rd Floor): 5:30 - 6:00 PM

**DAY 3: Wednesday, July 12, 2017**
Chairman: R. Chaguturu Co-Chairman: N.H. Greig		JOINT PLENARY SESSION ::: Location: Essex Center ::: 3^rd Floor
Time	Speakers	Titles
9:00 - 9:45 am	*PL-82* Ferid Murad (Nobel Laureate)	*Application of Nitric Oxide Research to Drug Development*
9:45 - 10:30 am	*PL-83* Alexander D. MacKerell, Jr.	*Can CADD Drive Drug Design and Development? Rapid Estimation of Relative Binding Affinities Based on Pre-Computed Ensembles*
10:30 - 11:15 am	*PL-84* D.K. Lahiri	*Role of Non-coding RNAs in Alzheimer’s Disease*
POSTER SESSION: 11:15 – 12:15 PM: (Location: Essex North West & Center – 3^rd Floor) LUNCH BREAK: 12:15 – 1:15 PM: (Location: Essex South – 3^rd Floor)

Locations	Lecture Hall St. George A & B 3^rd Floor	Lecture Hall St. George C 3^rd Floor	Lecture Hall St. George D 3^rd Floor
Tracks	Hot Topics in Medicinal Chemistry	CNS Drug Discovery & Therapy	Industrial & Manufacturing
	Hot Topics in Medicinal Chemistry		Medical Biotechnology
	Drug Discovery in Preclinical Research		Medical Biotechnology
			Nano Biotechnology
			Food Biotechnology
Chairman: P. Seneci Co-Chairman: S. Harper		Chairman: D.K. Lahiri Co-Chairman: R. Yan	Chairman: A.S. Mustafa Co-Chairman: K. Opwis
1:15 - 1:45 pm		1:15 - 1:45 pm	1:15 - 1:35 pm
*IL-85* Pierfausto Seneci *Function-oriented Synthesis (FOS), Rational Design and Serendipity: The AZA-tanshinone Story*		*IL-86* Cynthia Ann Lemere *Targeting a Pathogenic Seed, PyroGlu3 Ab, in Alzheimer’s Disease*	*SL-87* Klaus Opwis *Textile-fixed (Bio-) Catalysts*
1:45 - 2:15 pm		1:45 - 2:15 pm	1:35 - 1:55 pm
*IL-88* Hidayat Hussain *New Strategies to Generate New Chemical Diversity for Drug Discovery*		*IL-89* Nigel H. Greig *Proinflammatory* *Cytokine Inhibitors for the Treatment of Neurodegenerative Disorders*	*SL-90* Zayniddin Muhidinov *Fat and Waxes - Other Valuable Products from Plant Processing*
2:15 - 2:35 pm		2:15 - 2:45 pm	1:55 - 2:15 pm
*SL-91* Toshiaki Matsubara *An Insight into the Mechanism of the Electron-Transfer Induced Repair of the (6-4) T-T Photoproduct of DNA by the Photolyase. A Computational Study*		*IL-92* Jack Timothy Rogers *Cooperative RNA Modulation to Improve Iron Homeostasis Specific to Neurons while Providing Anti-amyloid Efficacy as a Potential Alzheimer’s Disease Therapy*	*SL-93* Muhammad Nauman Aftab *Optimization of Saccharification Potential for Plant Biomass of Recombinant Hemicellulases from Bacillus licheniformis ATCC 14580*
2:35 - 2:55 pm		2:45 - 3:15 pm	2:15 - 2:45 pm
*SL-94* Daniele Passarella *Self-assembling Drug-conjugates for Anti-cancer Targeting and Treatment*		*IL-95* Kumar Sambamurti *A Complex Cascade of Production and Degradation Determines the Yield of Aβ Yield In vivo*	*IL-96* Ipsita Roy *Natural Polymers of Bacterial Origin and Their Medical Applications*
2:55 - 3:15 pm		3:15 - 3:35 pm	2:45 - 3:05 pm
*SL-97* Andrea Cavalli *Synthetic Lethality Triggered by Combining Olaparib with BRCA2-RAD51 Disruptors*		Debomoy K. Lahiri *“View of the ROAD from the CAR- 2017” View of Research On Alzheimer’s Disease (ROAD) from the Current Alzheimer Research (CAR)* *(10 Minutes Coffee Break)*	*SL-98* Mehmet Sami Serin *Biomarker Potential of Several MiRNAs for the Early Diagnosis of Hepatocellular Carcinoma Related with HBV and HCV Infections*
3:15 - 3:35 pm		3:35 - 3:55 pm	3:05 - 3:25 pm
*SL-99* Aramini Andrea *TRPM8 Blockers: Rational Design of Novel Potent and Selective Small Molecule Chemical Series for Neuropathic Pain Relief*		*SL-100* Benjamin Wolozin *Stress Granules and Neurodegeneration: Novel Targets for Therapy in Amyotrophic Lateral Sclerosis and Alzheimer’s Disease*	*SL-101* Abu Salim Mustafa *Genomic Characterization of Brucella Strains Isolated from Human Brucellosis Patients in Kuwait*
3:35 - 3:55 pm		3:55 - 4:15 pm	3:25 - 3:45 pm
SL-102 Steven Harper *Selective HDACI’s for Non-Oncological Applications*		*SL-103* William Andrew Kofke *Functional Genomics in Human Brain Ischemia*	*SL-104* Thurai Moorthy *Molecular DX: Meeting Clinical Expectations*
3:55 - 4:15 pm		4:15 - 4:35 pm	3:45 - 4:05 pm
*SL-105* Brijesh Rathi *Discovery of Multistage Antimalarials: Synergistic Fusion of Privileged Bioactive Scaffolds Triggers Growth Inhibition of Malaria Parasite Plasmodium falciparum*		*SL-106* Horng-Jyh Harn *Targeting Therapy of Malignant Brain Tumor by a Local Interstitial Delivery System Loading with a Novel Small Molecule IND for Phase I/IIa Approved by FDA (IND 128388)*	*SL-107* Zaira Martín-Moldes *Design of Silk-chimera Biomaterial Bioinorganic Interfaces Related to Mineralization*
4:15 - 4:35 pm		4:35 - 4:55 pm	4:05 - 4:25 pm
*SL-108* Christine Gravier-Pelletier *Bacterial Peptidoglycan, Still a Source of Inspiration Towards Antibiotics*		*SL-109* Nicolas Marie *The mGlu7 Receptor: A New Target in the Therapy of Opiates Addiction?*	*SL-110* Katja Skorb *Self-adaptive and Stimuli-responsive Hybrid Polyelectrolyte/semiconductor Biosystems*
4:35 - 4:55 pm		4:55 - 5:15 pm	4:25 - 4:45 pm
*SL-111* Mahboob Alam *Bioassay-guided Isolation of New Urease Inhibitors from Ferula narthex Boiss* *(Withdrawn)*		*SL-112* Colin Kelly Combs *Strategies for Inhibiting the Aβ-stimulated Microglial Signaling Response in Alzheimer’s Disease*	*SL-113* Armin Eilaghi *Brain Magnetic Susceptibility is Associated with Cognitive Impairment in a Community Volunteer Population*
4:55 - 5:15 pm		5:15 - 5:45 pm	4:45 - 5:05 pm
*SL-114* Juan Jesus Perez *Identification of a Novel Inhibitory Allosteric Site of p38 MAP Kinase*		*IL-115* Riqiang Yan *Inhibition of BACE1 for Alzheimer’s therapy: Lessons from Conditional Deletion of BACE1 in AD Mouse Models*	*SL-116* Shiwen Huang *Improvement of Agrochemicals Performance by Nanotechnology and its Application in Agriculture*
5:15 - 5:35 pm		5:45 - 6:05 pm	5:05 - 5:15 pm
*SL-117* Reggie Yadao Dela Cruz *Antioxidant, Anti-inflammatory and Anticancer Potentials of Philippine Ferns and Lycopods*		*SL-118* Xudong Huang *Machine Learning-based Classification of FDG-PET Images from ADNI Database*	*SL-119* Sujata Mohanty *Effect of Environment and Growth Phase on Curcumin Production and Differential Gene Expression in Cu*
		6:05 - 6:25 pm
		*SL-120* Debjani Roy *Epigenetics in Alzheimer’s Disease: The Computational Systems Biology Paradigm for Understanding the epigenetic-based Markers and Drugs*
COFFEE BREAK (Location: Essex Foyer – 3^rd Floor): 5:00 - 6:00 PM

**DAY 4: Thursday, July 13, 2017**
Chairman: R. Kumar Co-Chairman: S.S. Hasnain		JOINT PLENARY SESSION ::: Location: Essex Center ::: 3^rd Floor
Time	Speakers	Titles
9:00 - 9:45 am	*PL-121* Vladimir Torchilin	*Stimuli-sensitive Multifunctional Combination Nanopreparations of siRNA and Chemotherapeutic Drugs to Treat Multidrug Resistant Cancer*
9:45 - 10:30 am	*PL-122* Steven A. Carr	*Quantitative Proteomics in Biology, Chemistry and Medicine*
10:30 - 11:15 am	*PL-123* Stuart L. Schreiber	*Chemistry Towards Novel Mechanism-of-action Compounds in Therapeutics Discovery*
POSTER SESSION: 11:15 – 12:15 PM: (Location: Essex North West & Center – 3^rd Floor) LUNCH BREAK: 12:15 – 1:15 PM: (Location: Essex South – 3^rd Floor)

Locations	Lecture Hall St. George A & B 3^rd Floor	Lecture Hall St. George C 3^rd Floor	Lecture Hall St. George D 3^rd Floor
Tracks	Structural Biology	Cancer Targeted Drug Delivery / Cancer Biomarkers	Inflammation and Immunology
	Hot Topics in Natural Products	Nutraceutical Drug Discovery & Therapy
Chairman: G-L. Hsu Co-Chairman: ???		Chairman: D. Dinulescu Co-Chairman: S.R. Setlur	Chairman: S.T. Sonis Co-Chairman: S. Huang
1:15 - 1:50 pm		1:15 - 1:50 pm	1:15 - 1:45 pm
*KNL-124* S. Samar Hasnain *Structure Based Approach in Drug Discovery and Identification of Ligand Binding Sites*		*KNL-125* Rakesh Kumar *ERBB2 Transcriptome: From Biology to Genomics to Biology*	*IL-126* Stephen Thomas Sonis *Opportunities for Target Identification to Prevent and Treat Cancer Regimen-related Toxicities*
1:50 - 2:10 pm		1:50 - 2:10 pm	1:45 - 2:05 pm
*SL-127* Nevim Aygun *Non-B DNA Structures as Candidate Drug Targets Against Structural Chromosomal Instability* *(Withdrawn)*		*SL-128* Daniela Dinulescu *Predictive and Prognostic Biomarkers for Chemoresistance in Ovarian Cancer*	*SL-129* Oreola Donini *Modulation of Innate Immunity in the Treatment of Inflammation-driven and Infection-driven Disease*
2:10 - 2:30 pm		2:10 - 2:30 pm	2:05 - 2:25 pm
*SL-130* Balasundaram Padmanabhan *Structure-based Drug Discovery of Small Molecule Modulators for Human Superoxide Dismutase I (hSOD1) Associated with ALS* *(Doubtful)*		*SL-131* Sunita Ramakrishna Setlur *Early MicroRNA Biomarkers of High Grade Serous Ovarian Cancer*	*SL-132* Gregory Zugates *An Inflammation-targeted Hydrogel Drug Delivery Platform: Application to Interstitial Cystitis*
2:30- 2:50 pm		2:30 - 2:50 pm	2:25 - 2:45 pm
*SL-133* Geng-Long Hsu *Discovery of a Natural Product for the Treatment of Erectile Dysfunction*		*SL-134* Hong Zhang *Metabotropic Glutamate Receptor 5 mediates the Suppressive Effect of 6-OHDA-induced Model of Parkinson’s Disease on Liver Cancer*	*SL-135* Michael Bonkowski *Protection from Radiation by Small Molecules That Raise NAD*
2:50- 3:10 pm		2:50- 3:10 pm	2:45- 3:05 pm
*SL-136* Geng-Long Hsu *A Compound Inhibits Jointly Phosphodiesterase 1 and 5*		*SL-137* Amr Amin *Development of a Therapeutic Model of Precancerous Liver Using Crocin-coated Magnetite Nanoparticles*	*SL-138* Dominic Richard Beal *Murine Models of GVHD – Modifications and Enhancements to Improve Reliability and Translatability*
3:10- 3:30 pm		3:10- 3:30 pm	3:05- 3:25 pm
*SL-139* Fatema Habeeb *A mixture of Camel Milk and Urine Shows Anticancer Properties in vitro and in vivo: An Evidence of a Traditional Ethnomedicine Practice*		*SL-140* Chandrakanth Emani *Basil, Ginger, Neem and Tobacco Extracts as Alternative and Integrative Treatment Options for Cancer*	*SL-141* Arthur P. Bertolino *Brilacidin, A Novel Anti-inflammatory Drug Candidate: Shows Potential Benefit in Both Severe Oral Mucositis and in Inflammatory Bowel Disease***
		3:30- 3:50 pm	3:25- 3:45 pm
		*SL-142* Waseem Hassan *Effect of Co-60 Gamma Radiation on Physicochemical Properties of Stored Peach (Prunus persica)*	*SL-143* Robert A. Beardsley *Pentaaza* *macrocycles reducing toxicity and increasing efficacy of radiation therapy*
COFFEE BREAK (Location: Essex Foyer – 3^rd Floor) : 3:30 - 4:00 PM
CASH PRIZE ANNOUNCEMENT FOR THE BEST POSTER AT 4:15 PM Location: Essex South (3rd Floor) (Poster Presenter’s Presence is Essential to Receive the Cash Award and Certificate of Merit) *PL: Plenary Lecture ::: KNL: Key Note Lecture ::: IL: Invited Lecture ::: SL: Session Lecture*